07 November 2025
: Case report 
Navigating Diagnostic Challenges in Pseudoachalasia: A Case Study of Esophagogastric Junction Adenocarcinoma
Unusual clinical course, Challenging differential diagnosis
Thanh Huu Nguyen
ABCDEF 1, Thang Quoc Le ABE 2, Muoi Xuan Nguyen ADE 1*, Ha Van Quoc BDE 1, Thinh Van Quoc Tran BDE 2, Pham Thi Thu Huong BCE 2, Ta Que Phuong BEF 1, Bui Chi Nam BEF 1, Pham Duc Huan ADE 3
DOI: 10.12659/AJCR.948966
Am J Case Rep 2025; 26:e948966
Figure 1 Initial imaging modalities: (A, esophagus) and (B, stomach). EGD showed difficulty passing through the esophagogastric junction (EGJ) (A, yellow arrow: constricted region), with no other abnormalities noted in the esophagus or stomach; (C) The chest X-ray revealed an 8- to 10-mm nodule (A red arrow) with no clear margin on the upper left lung; (D) High-resolution manometry (HMR) suggested an esophagogastric junction outflow obstruction (Chicago version 3).