Figure 1 Radiology patterns at baseline, in interim analysis and in final analysis (A–C) Maximum intensity projection (MIP) images of the patient at baseline, in interim analysis, and in final analysis. (D, E) Sagittal section of PET-CT fused images of the patient at baseline and in interim analysis. The elevated glucose uptake (maximum of standard uptake value [SUVmax] 21.0) of multiple enlarged lymph nodes and extensive extranodal lesions, including bilateral mammary gland, stomach, bilateral adrenal glands, uterus, left chest wall, interval of medial and lateral pterygoid, and multiple bones in MIP image at baseline (A) were greatly reduced in MIP image in interim analysis (SUVmax 1.5, Deauville 5-point scale 2 points) (B) and in final analysis (SUVmax 1.3, Deauville 5-point scale 2 points) (C). The representative enlarged retroperitoneal lymph node (81.0×53.0 mm) (red arrow) in PET-CT fused image at baseline (D) regressed as shown in PET-CT fused image in interim analysis (E).