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24 September 2025 : Case report  China

Efficacy of Pola-R-CHP and Autologous Stem Cell Transplantation in Untreated Burkitt Lymphoma: A Case Report

Unusual clinical course, Unusual setting of medical care

Yang Yang BEF 1, Yuhong Ren ORCID logo BDE 1, Jing Li B 1, Peng Liu AD 1*

DOI: 10.12659/AJCR.948969

Am J Case Rep 2025; 26:e948969

Figure 2 Pathological features of abdominal mass biopsy indicated the diagnosis of Burkitt lymphoma in this case. (A) Sheets of monotonous intermediate-size neoplastic B cells (black arrows) with starry sky appearances (benign macrophages containing ingested cellular debris, red arrows) in hematoxylin and eosin staining (400×). The neoplastic B cells were characterized by CD20+ (B)/CD10+ (C)/Bcl-2- (D)/Bcl-6+ (E), with a high Ki-67 proliferation index (90%+, F) (B–F 200×). c-Myc expression was positive on neoplastic B cells (G) (200×). (H) Fluorescence in situ hybridization indicated cells of MYC-IGH translocation (a pattern of red/green fusions, white arrow).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923