18 December 2025
: Case report 
Drug-Induced Lupus Erythematosus After 14 Years of Carbamazepine Use in a Patient With Neuromyelitis Optica Spectrum Disorder: A Case Report
Challenging differential diagnosis, Adverse events of drug therapy
Naho Ayuzawa-Takeda ABCDEF 1, Keisuke Saito ABCDE 2, Hidetoshi Yanagida ABCD 1, Tomoko Oeda ABCDEF 2*DOI: 10.12659/AJCR.949233
Am J Case Rep 2025; 26:e949233
Figure 3 Clinical course of the patient. Timeline depicting the patient’s clinical course, including onset and progression of systemic symptoms, CRP levels, and anti-DNA antibody titers before and after discontinuation of carbamazepine. After carbamazepine withdrawal, systemic symptoms resolved; CRP levels and anti-DNA antibody titers both decreased. CRP – C-reactive protein; NMOSD – neuromyelitis optica spectrum disorder.