29 September 2025
: Case report 
Complex Ocular Adverse Events Following Oxaliplatin Treatment: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Chao-Yang Zhao ABCEF 1, Chang-Sheng Liao BCF 2, Zi-You Yuan BE 1, Chen-Yue Zhao EF 3, Shao-Feng Hao
E 1, Hui-Lin Li ABD 1*
DOI: 10.12659/AJCR.949346
Am J Case Rep 2025; 26:e949346
Figure 1 Ocular imaging findings in oxaliplatin-induced ocular toxicity. (A) Anterior segment photography: Small avascular iris cysts are visible at the pupillary margins of both eyes. (B) Ultrasound biomicroscopy (UBM): Hypoechoic masses are detected posterior to the iris and anterior to the ciliary body, consistent with iris cysts. (C) B-Scan Ultrasonography: Bilateral retinal detachment with subretinal fluid accumulation is confirmed. (D) Optical coherence tomography (OCT): Shallow foveal detachment with granular intraretinal hyperreflectivity is observed in the macular region. (E) Ultra-widefield fundus photography: Blurred optic disc margins and tortuous retinal vessels are noted, with subretinal fluid involving the macula.