09 October 2025
: Case report 
Successful Management of Refractory Pulmonary Mucormycosis Using Intracavitary Amphotericin B: A Case Report and Literature Review
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Educational Purpose (only if useful for a systematic review or synthesis)
Yujie Gao ADEF 1,2, Hansheng Wang
CEF 1,2, Xiao feng Bai C 2, Yi Wu B 2, Xiaobing Li E 2, Meifang Wang CE 1,2, Fahim kanani E 1,2*
DOI: 10.12659/AJCR.949413
Am J Case Rep 2025; 26:e949413
Figure 1 Chest imaging examination. (A) Chest CT on 12 June suggests multiple inflammatory lesions (possibly fungal) in both lungs; (B) Chest CT on 16 June; (C) Chest CT on June 26 suggests multiple inflammatory lesions in both lungs and a small amount of pleural effusion on the left side; (D) Chest CT on 6 July showed that the lung lesions were roughly the same as before. This was a follow-up after intravenous infusion of amphotericin B and intravenous posaconazole; (E) Chest CT on 31 July showed that some lesions were smaller than before, and the pleural effusion on the left side was less than before. This was a follow-up after the first CT-guided intrapulmonary injection of amphotericin B; (F) Chest CT on 17 August showed that the lesions in both lungs were significantly smaller than before. This was a follow-up after the second CT-guided intrapulmonary injection of amphotericin B.