Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a  Response to Intravenous Immunoglobulin Therapy

Fajer Saleh Almeer; Heba Khalid Alkoheji; Marwa Ebrahim Zayed; Ali Jaffar Al-Hilly; Omar Abduljabar Hussein

doi:10.12659/AJCR.949542

12 February 2026 : Case report Bahrain

Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a Response to Intravenous Immunoglobulin Therapy

Challenging differential diagnosis, Rare disease

Fajer Saleh Almeer^{ABCDEFG 1*}, Heba Khalid Alkoheji^{ABCDEFG 2}, Marwa Ebrahim Zayed^{ABCDEFG 3}, Ali Jaffar Al-Hilly^{ABCDEFG 3}, Omar Abduljabar Hussein^{ABCDEFG 3}

DOI: 10.12659/AJCR.949542

Am J Case Rep 2026; 27:e949542

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Figure 2 Bilateral thalamic and periventricular hyperintensity on T2-weighted fluid-attenuated inversion recovery sequences (FLAIR)Axial T2-weighted FLAIR sequences demonstrate symmetric, bilateral areas of high signal intensity involving the thalami (red arrows) and periventricular white matter (blue arrows).

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Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a Response to Intravenous Immunoglobulin Therapy

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