Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a  Response to Intravenous Immunoglobulin Therapy

Fajer Saleh Almeer; Heba Khalid Alkoheji; Marwa Ebrahim Zayed; Ali Jaffar Al-Hilly; Omar Abduljabar Hussein

doi:10.12659/AJCR.949542

12 February 2026 : Case report Bahrain

Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a Response to Intravenous Immunoglobulin Therapy

Challenging differential diagnosis, Rare disease

Fajer Saleh Almeer^{ABCDEFG 1*}, Heba Khalid Alkoheji^{ABCDEFG 2}, Marwa Ebrahim Zayed^{ABCDEFG 3}, Ali Jaffar Al-Hilly^{ABCDEFG 3}, Omar Abduljabar Hussein^{ABCDEFG 3}

DOI: 10.12659/AJCR.949542

Am J Case Rep 2026; 27:e949542

Authors information Article notes Copyright and License information

Introduction Case Report Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Figure 3 Pontine hyperintensity on T2-weighted fluid-attenuated inversion recovery sequences (FLAIR)Axial T2-weighted FLAIR sequences show an area of high signal intensity within the pons region of the brainstem (red arrow), indicating inflammatory edema. Brainstem involvement is a characteristic feature of acute hemorrhagic necrotizing encephalitis and is associated with more severe disease.

Back to the Article

Acute Hemorrhagic Necrotizing Encephalopathy in a COVID-19 Patient With a Response to Intravenous Immunoglobulin Therapy

Your Privacy