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22 November 2025 : Case report  China

Sodium Valproate-Associated Thrombocytopenia in Antiepileptic Drug Polypharmacy: A Case Report and Review of the Literature

Diagnostic / therapeutic accidents, Adverse events of drug therapy

Xuehua Deng CEF 1, Xinyi Tu CEF 1, Shiwen Yang BD 1, Jianghong Xiong BD 1, Yuanjian Yang ADFG 1,2, Shuzhen Jiang ABD 1,2*

DOI: 10.12659/AJCR.949595

Am J Case Rep 2025; 26:e949595

Figure 1 Trends in RBC counts, Hb level, and PLT count (upper panel) and medication records (lower panel) during the treatment period. The dotted lines indicate the lower reference range limit for each parameter. bid – twice daily; Hb – hemoglobin; LEV – levetiracetam; PLT – platelets; qd – once daily; RBC – red blood cell; tid – 3 times daily; VPA – valproate.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923