05 March 2026
: Case report 
Leukocytoclastic Vasculitis Induced by Dalbavancin: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Rare disease
Vincenzo Scaglione
EF 1*, Marco Cola E 1, Lolita Sasset E 1, Francesco Fortarezza BD 2, Carla Casarin EF 1, Marco Trevenzoli AD 1, Angelo Paolo Dei Tos BD 2,3, Annamaria Cattelan ADEF 1,4
DOI: 10.12659/AJCR.949653
Am J Case Rep 2026; 27:e949653
Figure 2 Histological image of the skin biopsy showing a perivascular inflammatory infiltrate in the superficial dermis associated with red blood cell extravasation (A, hematoxylin and eosin, original magnification ×100). The inflammatory infiltrate is composed of lymphocytes, neutrophils, and eosinophils and is associated with vascular wall destruction with fibrinoid necrosis (black arrows), and involvement of eccrine glands (yellow arrow) (B, hematoxylin and eosin, original magnification ×200). In the last image, karyorrhexis and nuclear dust can be appreciated (C, hematoxylin and eosin, original magnification ×200). Overall, these morphological findings are consistent with leukocytoclastic vasculitis.