09 December 2025
: Case report 
Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom
Unknown etiology, Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care, Rare disease, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology
Caroline Evanthe Nathania
ABCDEF 1, Astuti Prodjohardjono ACDEF 2,3, Noor Alia Susianti ABCDEF 2*, Abdul Gofir DEF 2,3, Cempaka Thursina Srie Setyaningrum DEF 2,3, Kamala Kan Nur Azza EF 4,5, Ahmad Asmedi F 2,3, Sri Sutarni F 2,3
DOI: 10.12659/AJCR.949699
Am J Case Rep 2025; 26:e949699
Figure 3 Sagittal view (A) demonstrates bilateral parietal lobe atrophy (yellow arrows) suggesting vascular compromise in watershed areas, a finding commonly associated with Behçet’s Disease. Coronal view (B) confirms normal hippocampal anatomy (blue arrows), helping to exclude Alzheimer’s disease as a primary etiology. The transversal T2-weighted image (C) shows mild hyperintensities in the temporal lobes (red arrows), corresponding to a Fazekas score of 1, which argues against significant small vessel disease and supports the exclusion of vascular dementia.