07 November 2025
: Case report 
Irritation Fibroma on the Tongue Tip Associated With Mandibular Incisors Diastema in a 53-Year-Old Woman: A Case Report
Mistake in diagnosis, Diagnostic / therapeutic accidents, Rare coexistence of disease or pathology
Alaa W. Alqutub
ABEF 1*, Abrar B. Alzahrani ABF 2, Sali A. Sayed ABF 2, Shumukh Y. Balhmer ABF 2, Wareef O. Ghazzawi ABF 2, Abrar K. Demyati ABEF 1
DOI: 10.12659/AJCR.949736
Am J Case Rep 2025; 26:e949736
Figure 4 Photomicrograph of the histopathology of an irritation fibroma excised from the tip of the tongueThe histology demonstrates hyperplastic keratinizing stratified squamous epithelium with elongated rete ridges overlying a dense collagenous stroma containing scattered fibroblasts. Chronic inflammatory cells, including lymphocytes and plasma cells, are sparsely present. Findings are consistent with a benign irritation fibroma. Hematoxylin and eosin [H&E] stain. Magnification ×40.