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07 December 2025 : Case report  Thailand

Acute Kidney Injury from Mononuclear Cell-Predominated Interstitial Nephritis After Introduction of a Glucagon-Like Peptide-1 Receptor Agonist: A Case Report

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease, Adverse events of drug therapy

Raweekarn Itsathitpaisarn BF 1, Nattavong Suksawad F 2, Watsapol Wongwikrom F 2, Jerasit Surintrspanont ORCID logo B 3,4, Thana Thongsricome ORCID logo AE 1,5*

DOI: 10.12659/AJCR.949913

Am J Case Rep 2025; 26:e949913

Figure 2 Light microscopy kidney biopsy results. Features of diabetic nephropathy are shown in Figure A (PAS, 40×) – B (Jones, 40×): nodular sclerosis of the glomeruli and thickened tubular basement membrane, and C (PAS, 40×): thickened tubular basement membrane and hypertensive change of the renal artery. Figure D (H&E, 10×) and E (H&E, 100×) depict interstitial infiltration with lymphocyte predominance and scarce eosinophils. Scale bars denote 0.1 mm. H&E – hematoxylin and eosin stain; PAS – periodic acid-Schiff.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923