21 November 2025
: Case report 
Left-Sided Perforated Appendicitis in an Elderly Man with Intestinal Malrotation: A Case Report
Challenging differential diagnosis, Management of emergency care, Congenital defects / diseases, Educational Purpose (only if useful for a systematic review or synthesis)
Jose Samaniego-Burneo
ABCE 1,2,3, Jordan Llerena-Velastegui ACDEF 1,2,3,4*, Alberto Gordillo-Calero ACF 3, Brenda Santamaria-Penafiel DEF 2,3, Natalia Lopez-Yepez BCD 5
DOI: 10.12659/AJCR.949960
Am J Case Rep 2025; 26:e949960
Figure 4 Histopathologic examination (hematoxylin and eosin stain, original magnification ×10) demonstrating extensive transmural necrosis, dense neutrophilic infiltrate, serosal fibrin deposition, and areas of preserved mucosa and muscularis propria, consistent with perforated phase IV acute appendicitis with abscess formation.