09 February 2026
: Case report 
Successful Treatment of Multifocal Demyelinating Sensory-Motor Neuropathy (Lewis-Sumner Syndrome) With Rituximab: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Mengcui Gui BCEF 1,2, Jing Lin BF 1,2, Yue Li
B 1,2, Bo Chen B 1,2, Bitao Bu AG 1,2, Zhijun Li AFG 1,2*
DOI: 10.12659/AJCR.950084
Am J Case Rep 2026; 27:e950084
Figure 5 Left sural nerve biopsy showed a mild reduction in myelinated nerve fibers within the nerve bundles, with demyelination changes (arrow) and axonal degeneration (triangle). Some axons appear to have slightly increased diameters, with the formation of medullary globules. No obvious onion bulb-like changes were observed. (A) H&E stain, ×100; (B) NF stain, ×100; (C) MBP stain, ×100; (D) toluidine blue stain, ×100; (E) electron microscopy.