24 January 2026
: Case report 
Disseminated Histoplasmosis and Aortic Valve Infective Endocarditis in a Patient With Recent Aortobifemoral Bypass
Challenging differential diagnosis, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology
Habib Behjatnia ABCDEF 1, Patricia Couto CDE 2, Yiliam Castillo ACDE 2, Liorge Dominguez DEF 2, Stephen Carlan
BCEF 3*, Tamisha H. Guzman BCDE 4, Mark E. Jentoft BCDE 4
DOI: 10.12659/AJCR.950135
Am J Case Rep 2026; 27:e950135
Figure 4 Histopathological analysis of the aortic valve: (A, B) Hematoxylin and eosin–stained cross-sections show vegetation (A, 40× magnification; B, 100× magnification). (C) Grocott methenamine silver stain highlights fungal organisms (100× magnification). Gram stain (D, 100× magnification) and acid-fast bacilli stain (E, 100× magnification) results are negative, excluding bacterial and mycobacterial organisms.