28 November 2025
: Case report 
Persistent Primitive Hypoglossal Artery in a 55-Year-Old Woman with Recurrent Dizziness, Identified on Ultrasound and Computed Tomography Imaging
Challenging differential diagnosis, Rare disease
Weiwei Zhang EFG 1, Zhenli Huang EFG 1, Liya Wei BF 1, Yanrong Sun ACD 1*, Fei Sang ACD 2DOI: 10.12659/AJCR.950244
Am J Case Rep 2025; 26:e950244
Figure 1 Carotid Doppler ultrasound (CDU) of left-sided Persistent Primitive Hypoglossal Artery (PPHA) in a 55-year-old woman. (A) shows a dilated left internal carotid artery (ICA, white arrow) with an anomalous branch at its distal end (red arrow), (B) displays increased peak systolic velocity of the left ICA, (C, E) present hypoplastic bilateral vertebral arteries (VAs, white arrows), and (D, F) reveal high-resistance flow patterns in the bilateral VAs, all consistent with CDU findings suggestive of PPHA.