16 February 2026
: Case report 
Left-Sided Portal Hypertension Induced by Splenic Arteriovenous Malformation: A Case Report
Unknown etiology, Challenging differential diagnosis, Rare disease
Shenghao Zhang ABCDEF 1, Hao Li BCD 2, Guoliang Cao ABC 1, Ying Mei BCD 3, Yang Huang BCD 1, Mingjie Zhang ABCD 1*DOI: 10.12659/AJCR.950381
Am J Case Rep 2026; 27:e950381
Figure 6 Histopathological Imaging. (A) splenic arteriovenous malformation: HE stain (left) and elastic fibers stain (right). (B) Altered subintimal lipid deposition in veins: HE stain (left) and elastic fibers stain (right), lipidoses (black arrow), calcification (red arrow). (C) Rupture of the internal elastic membrane in the artery: HE stain (upper) and elastic fibers stain (bottom). (D) Intravenous multilayer discontinuous elastic fibers: HE stain (upper) and elastic fibers stain (bottom). (E) Vascular IgG4 immunohistochemistry negative: IgG stain (upper left), IgG4 stain (upper right), Lambda-Light Chain stain (bottom left), Kappa-Light Chain stain (bottom right).