02 February 2026
: Case report 
Neoadjuvant Pressurized Intraperitoneal Aerosol Chemotherapy for Conversion to Cytoreductive Surgery in Unresectable Malignant Peritoneal Mesothelioma: A Report of 2 Cases
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Arnaldo Urbano-Ruiz ABCDEF 1*, Bruna Latronico Palma ABCDEF 1, Ronaldo Elias Carnut Rego F 1, Daniel Bianqui Guaraldo da Silva
F 1, Bianca Fava F 1, Erlan Araujo Falcão F 1, Michelle Louise Rodrigues Barbosa da Silva F 1, Julia Rodrigues Leandro Uliano F 1
DOI: 10.12659/AJCR.950407
Am J Case Rep 2026; 27:e950407
Figure 1 Initial intraoperative appearance of Patient 1 during cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), demonstrating a broad desmoplastic reaction of the greater omentum (arrow) following pressurized intraperitoneal aerosol chemotherapy (PIPAC) cycles.