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25 November 2025 : Case report  Japan

Full-Thickness Macular Hole After Faricimab Treatment for Branch Retinal Vein Occlusion-Associated Macular Edema with Vitreomacular Traction: A Case Report

Unusual clinical course, Unusual or unexpected effect of treatment

Hiroki Sano ORCID logo ABDEF 1*, Ryoji Yanai ORCID logo ADEF 2, Yoshinori Mitamura ADEF 2

DOI: 10.12659/AJCR.950495

Am J Case Rep 2025; 26:e950495

Figure 2 Macular thickness changes on OCT map and ETDRS grids before and after intravitreal faricimab injection.(A) OCT thickness map at presentation showing prominent CME that extends from the superior parafoveal region to the foveal center. (B) ETDRS 9-sector grid at presentation showing pronounced thickening in the central and superior subfields. (C) OCT map 1 week after injection showing partial reduction of edema, particularly in the superior parafoveal region. (D) ETDRS grid 1 week after injection showing decreased thickness in the central and superior subfields, although overall thickness remains greater than normal. (E) OCT map 1 month after injection showing further reduction of edema in the superior parafoveal region; thickness remains elevated. (F) ETDRS grid 1 month after injection showing persistent but reduced thickening in the central and superior subfields. CME – cystoid macular edema; ETDRS – Early Treatment Diabetic Retinopathy Study; OCT – optical coherence tomography.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923