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25 November 2025 : Case report  Japan

Full-Thickness Macular Hole After Faricimab Treatment for Branch Retinal Vein Occlusion-Associated Macular Edema with Vitreomacular Traction: A Case Report

Unusual clinical course, Unusual or unexpected effect of treatment

Hiroki Sano ORCID logo ABDEF 1*, Ryoji Yanai ORCID logo ADEF 2, Yoshinori Mitamura ADEF 2

DOI: 10.12659/AJCR.950495

Am J Case Rep 2025; 26:e950495

Figure 3 Postoperative changes after vitrectomy and FTMH closure.(A) Fundus photograph at 1 week postoperatively showing residual intraretinal hemorrhage and intraocular gas tamponade. (B) Horizontal OCT scan at 1 week postoperatively showing FTMH closure. (C) Vertical OCT scan at 1 week postoperatively showing FTMH closure without clinically significant residual edema. (D) OCT thickness map at 1 week postoperatively showing reduced thickening in the superior parafoveal region compared with preoperative scans. (E) ETDRS 9-sector grid at 1 week postoperatively indicating decreased thickening in the superior subfield compared with preoperative findings. (F) Fundus photograph at 3 weeks postoperatively showing partial resolution of intraretinal hemorrhage and disappearance of intraocular gas. (G) Horizontal OCT scan at 3 weeks postoperatively showing recurrent retinal thickening compared with earlier postoperative scans, consistent with worsening macular edema. (H) Vertical OCT scan at 3 weeks postoperatively showing persistent FTMH closure with cystoid spaces in the inner nuclear layer. (I) OCT thickness map at 3 weeks postoperatively showing increased retinal thickness, particularly in the superior parafoveal region, indicating recurrence of macular edema. (J) ETDRS 9-sector grid at 3 weeks postoperatively showing persistent thickening in the superior parafoveal region and mild central thickening. ETDRS – Early Treatment Diabetic Retinopathy Study; FTMH – full-thickness macular hole; OCT – optical coherence tomography.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923