20 November 2025
: Case report 
Improvement in Chronic Atrophic Gastritis After Treatment with Zinc L-Carnosine
Unusual clinical course, Unusual or unexpected effect of treatment
Rudi De Bastiani B 1, Matteo Fassan
B 2,3, Gianluca Businello B 2, Antonio Tursi ACEF 4,5*
DOI: 10.12659/AJCR.950553
Am J Case Rep 2025; 26:e950553
Figure 2 Case 2. Representative images from the initial diagnosis (2022) showing severe atrophy in both the gastric antrum (A) and corpus (B) (hematoxylin and eosin [H&E], 5×) with focal intestinal metaplasia (Operative Link on Gastritis Assessment [OLGA] stage 3, higher magnification, H&E, 20×). Follow-up images (2024) demonstrate mild atrophy in the gastric antrum and angulus (C; H&E, 5×) with focal intestinal metaplasia (OLGA stage 1, higher magnification, H&E, 20×). A representative biopsy fragment of oxyntic mucosa at follow-up (D; H&E, 5×) shows no gastric atrophy; focal intestinal and pseudopyloric metaplasia (OLGA stage 1) was identified in 1 of 4 fragments (H&E, 20×).