26 December 2025
: Case report 
Primary Well-Differentiated Neuroendocrine Tumor of the Breast: A Case Report and Literature Review
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Patient complains / malpractice, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Sanjna Sai Gudena DEF 1*, Nilesh Digvijay Kashikar E 2, Matthew Charles Wakefield E 3DOI: 10.12659/AJCR.950684
Am J Case Rep 2025; 26:e950684
Figure 3 At a higher magnification (200×), the tumor cells show many typical features of neuroendocrine morphology. The tumor cells are polygonal with granular eosinophilic cytoplasm. The classical salt-and-pepper stippled chromatin is visible in a minority of tumor cells. Neuroendocrine tumors of the breast in general, as also seen in this case, tend to show a lower Nottingham nuclear grade of 1 or 2 out of 3.