22 April 2026
: Case report 
Diagnostic Approaches to Adult Cystic Nephroma: Insights From Two Cases
Challenging differential diagnosis, Rare disease
Madalina Bosoteanu AE 1,2, Raluca Ioana Vodă EF 3,4*, Cristian Ionut Orășanu
EF 1,4, Luana-Andreea Nurla EF 5, Nicolae Ciufu BE 6,7
DOI: 10.12659/AJCR.950808
Am J Case Rep 2026; 27:e950808
Figure 5 Immunohistochemical features of case 2. (A) Positive staining for paired box gene 8 (PAX8) in cystic epithelial cells and septal tubular/microcystic structures (red arrow) (200× magnification). (B) Positive staining for smooth muscle actin (SMA) in stromal cells (200× magnification). (C) Positive nuclear staining for estrogen receptor (ER) in stromal structures (200× magnification). (D) Positive nuclear staining for Ki-67 in 1% of tumor cells (red circles) (200× magnification).