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05 March 2026 : Case report  Poland

Bilateral Eales’ Disease Managed With Vitrectomy and Anti-VEGF Therapy: A Case Report

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Zuzanna Lelek ORCID logo ABCDEF 1, Martyna Machaj ORCID logo ABCDEF 1, Katarzyna Krysik ORCID logo F 1,2, Dominika Janiszewska-Bil ORCID logo E 1,3, Dariusz Dobrowolski ORCID logo F 1,4,5, Sylwia Ewa Szendzielorz-Krzempek B 6, Beniamin Oskar Grabarek ORCID logo EF 3,7, Anita Lyssek-Boroń ORCID logo DE 1,2*

DOI: 10.12659/AJCR.950820

Am J Case Rep 2026; 27:e950820

Figure 2 Optical coherence tomography (OCT) and retinal thickness maps after treatment. The Comprehensive Retina Cube OU report presents macular cross-sectional OCT images, retinal thickness distribution, and ganglion cell complex (GCC) maps for the right eye (OD) and left eye (OS). Postoperative imaging demonstrates preserved retinal architecture, normal foveal contour, and stable central retinal thickness bilaterally, consistent with full functional recovery (best-corrected visual acuity 5/5; 0.00 logarithm of the minimum angle of resolution [logMAR] in both eyes). Baseline OCT images were available only for the right eye; dense vitreous hemorrhage precluded initial scanning of the left eye. Comparative improvement was most evident in the right eye, with postoperative normalization of central retinal thickness and resolution of exudates. Systemic immunosuppression via methotrexate (7.5 mg/week) was maintained after panretinal photocoagulation in the right eye.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923