24 April 2026
: Case report 
A 68-Year-Old Man With Neutrophil-Rich Hepatoid Adenocarcinoma of the Gallbladder
Challenging differential diagnosis, Rare coexistence of disease or pathology
Mingxia Chen
ABCDEF 1*, Fanhong Kong BCEF 1, Min Wang BC 1, Yuanyuan Li B 1, Baojuan Gao D 2
DOI: 10.12659/AJCR.950825
Am J Case Rep 2026; 27:e950825
Figure 4 Immunohistochemical and histochemical features of hepatoid adenocarcinoma of the gallbladder with neutrophilic infiltration: (A) Tumor cells diffusely express CK19 (immunohistochemistry [IHC], 400×). (B) Hepatoid cells are positive for hepatocyte paraffin 1(HepPar-1) (IHC×400). (C) Hepatoid cells are negative for CK7 (IHC 400×). (D) signet ring cells are positive for PAS-d (histochemical stains [HS] 400×).