13 March 2026
: Case report 
A Challenging Case of Pleomorphic Lipoma of the Shoulder Mimicking Liposarcoma
Challenging differential diagnosis
Yunan Han
DEF 1, Abid Qureshi ADEF 1, Haleigh M. Heubeck EF 1, Yingxian Liu ADEF 2, Luca Milone ABDEF 1*
DOI: 10.12659/AJCR.950876
Am J Case Rep 2026; 27:e950876
Figure 4 Histopathologic features of the excised soft tissue massLow-power view (hematoxylin and eosin, 40×) showing a lipomatous lesion composed of atypical spindle cells, some with marked pleomorphism and multinucleation (arrow), and variably sized adipocytes (arrow head) embedded within fibrotic and slightly myxoid stroma.