Perihilar Biliary Neuroendocrine Carcinoma Treated With Perioperative Chemotherapy and Radical Liver Surgery: A Thought-Provoking Case

Ryo Ataka; Kazuhiko Kitaguchi; Yusuke Nakayama; Yoshinobu Ikeno; Eiji Toyoda; Tetsuro Hirose

doi:10.12659/AJCR.951108

19 February 2026 : Case report Japan

Perihilar Biliary Neuroendocrine Carcinoma Treated With Perioperative Chemotherapy and Radical Liver Surgery: A Thought-Provoking Case

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Ryo Ataka

^{ABCDEF 1,2*}, Kazuhiko Kitaguchi^{AE 1}, Yusuke Nakayama^{AE 3}, Yoshinobu Ikeno^{AE 4}, Eiji Toyoda^{E 1}, Tetsuro Hirose^{E 1}

DOI: 10.12659/AJCR.951108

Am J Case Rep 2026; 27:e951108

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Figure 2 Endoscopic retrograde cholangiopancreatography and tumor biopsy. Perihilar biliary obstruction and severe occlusion of the left hepatic duct (arrow). Poorly differentiated cells with characteristic nuclear molding and extensive crush artifacts (inset).

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Perihilar Biliary Neuroendocrine Carcinoma Treated With Perioperative Chemotherapy and Radical Liver Surgery: A Thought-Provoking Case

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