07 January 2026
: Case report 
Fampridine in Hereditary Spastic Paraplegia Type 4 With SPAST Variant c.683-2A>C: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease
Josef Finsterer
ABCDE 1*
DOI: 10.12659/AJCR.951160
Am J Case Rep 2026; 27:e951160
Figure 1 Pedigree of the index patient’s family. The index patient is indicated by an arrow. She developed pollakiuria since age 34, mild paraparesis since age 53, hypoacusis since age 60, and myalgia and muscle cramps since age 62.