Co-Pathogenic Role of BRCA1 and OBSCN Deletions in Chinese Familial Breast Cancer: A Case Report

Lili Yi; Kexin Chen; Dandan Wang; Ruhao Wang; Xiaoru Zhu; Jian Chai; Xiaodong Jia; Fei Xu; Mingliang Gu; Chuanyou Cui; Wei Zhang

doi:10.12659/AJCR.951196

02 May 2026 : Case report China

Co-Pathogenic Role of BRCA1 and OBSCN Deletions in Chinese Familial Breast Cancer: A Case Report

Unknown etiology

Lili Yi^{BCDE 1}, Kexin Chen^{CEF 1}, Dandan Wang^{C 2}, Ruhao Wang^{D 1}, Xiaoru Zhu^{C 2}, Jian Chai^{G 1}, Xiaodong Jia^{CD 1}, Fei Xu^{DG 3}, Mingliang Gu^{AG 1}, Chuanyou Cui^{BE 4*}, Wei Zhang^{ADE 5}

DOI: 10.12659/AJCR.951196

Am J Case Rep 2026; 27:e951196

Authors information Article notes Copyright and License information

Introduction Case Report Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Figure 4 Sanger sequencing chromatograms for Patient III-14 showing heterozygous deletions in BRCA1, HMMR, and OBSCN, alongside the normal Sanger sequencing chromatograms for these 3 genes. The missing loci are marked (red arrow and red box).

Back to the Article

Co-Pathogenic Role of BRCA1 and OBSCN Deletions in Chinese Familial Breast Cancer: A Case Report

Your Privacy