Neuroendocrine Carcinoma of the Submandibular Gland in an Older Adult: A Rare Case and Literature Review

Rossana Moi; Ingrid Raponi; Alessandra Perfetti; Silvana Giacinti; Michele Battista; Piero Luigi Alò; Andrea Marzetti

doi:10.12659/AJCR.951324

26 April 2026 : Case report Italy

Neuroendocrine Carcinoma of the Submandibular Gland in an Older Adult: A Rare Case and Literature Review

Rare disease

Rossana Moi^{ABCDEFG 1}, Ingrid Raponi

^{ABCDEFG 1*}, Alessandra Perfetti^{BE 2}, Silvana Giacinti^{BE 3}, Michele Battista^{BE 4}, Piero Luigi Alò^{BE 2}, Andrea Marzetti^{ABCDEFG 1}

DOI: 10.12659/AJCR.951324

Am J Case Rep 2026; 27:e951324

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Introduction Case Report Discussion Conclusions References

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Figure 2 Contrast-enhanced axial computed tomography scan showing a large left submandibular mass characterized by a prominent central necrotic area. The lesion extends into the subcutaneous plane and appears closely adjacent to the left submandibular gland, without clear cleavage planes.

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Neuroendocrine Carcinoma of the Submandibular Gland in an Older Adult: A Rare Case and Literature Review

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