22 May 2026
: Case report 
Synchronous Isolated Cystic Pancreatic Metastasis Arising From Primary Colorectal Cancer: A Rare Case Report
Rare coexistence of disease or pathology
Reem Mubarak ABCDEFG 1*, Samah Mohamed
BE 2,3, Rajen Goyal B 1, Ibnouf Sulieman A 1, Walid Shehata A 1, Samir Al Hyassat BD 1, Ahmed Elaffandi ABCDEF 1
DOI: 10.12659/AJCR.951327
Am J Case Rep 2026; 27:e951327
Figure 4 Histologic images of the tumor in the Whipple resection: (A) Adenocarcinoma composed of fused, cribriform malignant glands with mucin (right) invading residual pancreatic parenchyma (left) (hematoxylin and eosin [H&E] stain, 40×). (B) Cribriform, back-to-back arrangement of adenocarcinoma glands with abundant extracellular mucin, consistent with metastasis from a colorectal primary (H&E, 100×). (C) Vascular invasion characterized by clusters of adenocarcinoma glands within a vessel (black arrow) (H&E, 200×). (D) Perineural invasion characterized by adenocarcinoma encroaching on a nerve structure (black arrow) (H&E, 200×).