16 March 2026
: Case report 
Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report
Challenging differential diagnosis, Rare disease, Rare coexistence of disease or pathology
Benjamin D. Lueck ABCDEF 1, Alyssa K.W. Maclean ABCDEF 1, Georges El Hasbani ABCDEF 2, Andrew J. Layman CDE 3, Floranne C. Ernste CDEF 2, Courtney A. Arment ABCDEFG 2*DOI: 10.12659/AJCR.951603
Am J Case Rep 2026; 27:e951603
Figure 2 Pathology from endomyocardial biopsy of the right ventricle. Images demonstrate marked myocyte hypertrophy with regions of pericellular interstitial fibrosis (hematoxylin-eosin, 100× original magnification). There was no significant inflammation (granulomatous or lymphocytic) and no viral cytopathic effect was identified. Focal areas of replacement-type fibrosis demonstrated macrophages and scattered loose pigment consistent with subacute myocardial injury (inset, hematoxylin and eosin, 400× original magnification).