16 March 2026
: Case report 
Fatal Cardiomyopathy Secondary to Seronegative Immune-Mediated Necrotizing Myopathy: A Case Report
Challenging differential diagnosis, Rare disease, Rare coexistence of disease or pathology
Benjamin D. Lueck ABCDEF 1, Alyssa K.W. Maclean ABCDEF 1, Georges El Hasbani ABCDEF 2, Andrew J. Layman CDE 3, Floranne C. Ernste CDEF 2, Courtney A. Arment ABCDEFG 2*DOI: 10.12659/AJCR.951603
Am J Case Rep 2026; 27:e951603
Figure 3 Pathology obtained at the time of autopsy. (A–C) Hematoxylin-eosin–stained samples of cardiac tissue demonstrating (A) widespread chronic scarring interspersed in the myocardial tissue, (B) fibrotic changes of the myocardium, and (C) a focus of chronic inflammation (asterisk). (D, E) Hematoxylin-eosin–stained samples of skeletal tissue showing (D) an area of necrosis within the skeletal muscle with loss of striated architecture and increased eosin uptake (arrow) and (E) interspersed regions of fibrosis within the skeletal muscle tissue. Courtesy of Dr. Ross E. Zumwalt, Department of Laboratory Medicine and Pathology, Mayo Clinic.