An Uncommon Presentation of Heyde Syndrome: Absence of Visible Endoscopic Angiodysplasia With Resolution After Transcatheter Aortic Valve Replacement

Ronnie A. Napoles; Cristina Benites; Gabriella Morey; Anthony H. Xu; Luis Santiago Zayas; Kristen Santana; Livasky Concepcion Perez

doi:10.12659/AJCR.951614

09 May 2026 : Case report USA

An Uncommon Presentation of Heyde Syndrome: Absence of Visible Endoscopic Angiodysplasia With Resolution After Transcatheter Aortic Valve Replacement

Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment

Ronnie A. Napoles^{ABCDEFG 1*}, Cristina Benites

^{ABCDEFG 2}, Gabriella Morey^{ABCDEFG 2}, Anthony H. Xu^{E 2}, Luis Santiago Zayas^{ABCDEFG 3}, Kristen Santana

^{ABCDEFG 3}, Livasky Concepcion Perez^{ABCDEFG 3}

DOI: 10.12659/AJCR.951614

Am J Case Rep 2026; 27:e951614

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Figure 1 Colonoscopy images demonstrating hematin (altered blood/coffee-ground-like material) throughout the examined colon. (A)4Hematin (altered blood/coffee-ground-like material; red arrows) coating the mucosal surfaces of the colon. (B) Hematin (red arrow) present in the intestinal lumen. (C) Hematin deposits (red arrows) throughout the examined colon, consistent with ongoing or recent gastrointestinal bleeding.

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An Uncommon Presentation of Heyde Syndrome: Absence of Visible Endoscopic Angiodysplasia With Resolution After Transcatheter Aortic Valve Replacement

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