09 May 2026
: Case report 
An Uncommon Presentation of Heyde Syndrome: Absence of Visible Endoscopic Angiodysplasia With Resolution After Transcatheter Aortic Valve Replacement
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
Ronnie A. Napoles ABCDEFG 1*, Cristina Benites
ABCDEFG 2, Gabriella Morey ABCDEFG 2, Anthony H. Xu E 2, Luis Santiago Zayas ABCDEFG 3, Kristen Santana ABCDEFG 3, Livasky Concepcion Perez ABCDEFG 3
DOI: 10.12659/AJCR.951614
Am J Case Rep 2026; 27:e951614
Figure 5 This flowchart outlines the process for evaluating, diagnosing, and treating HS. Following patient presentation, the procedure includes medical history assessment, physical examination, and laboratory testing. After imaging and endoscopic assessments, the severity of AS and the sources of gastrointestinal bleeding are established. Clinical observations, diagnostic data, echocardiography, and endoscopy support HS, while severe AS is managed with TAVR. The processes preceding and following TAVR include risk evaluation, anticoagulation management, and monitoring.