Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Xiaofeng Zhao

doi:10.12659/AJCR.951658

23 March 2026 : Case report USA

Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Unusual clinical course, Challenging differential diagnosis

Xiaofeng Zhao

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DOI: 10.12659/AJCR.951658

Am J Case Rep 2026; 27:e951658

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Figure 2 Histopathology findings of ultrasound-guided fine-needle aspiration (EUS-FNA) of the pancreas lesion. H&E staining revealed moderately differentiated adenocarcinoma at low power (100×, A) and high power (400×, B). The tumor cells show overlapping histology with the resected lung adenocarcinoma (400×, C and D).

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Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

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