Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Xiaofeng Zhao

doi:10.12659/AJCR.951658

23 March 2026 : Case report USA

Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

Unusual clinical course, Challenging differential diagnosis

Xiaofeng Zhao

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DOI: 10.12659/AJCR.951658

Am J Case Rep 2026; 27:e951658

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Figure 3 Immunohistochemical profiles of the pancreatic mass. The pancreas adenocarcinoma (A, H&E,100×) was positive for CK7 (B) and CA19.9 (C). CDX2 (D) is weakly and patchy positive. TTF-1 shows non-specific cytoplasmic staining (E), but napsin A was positive (F) in tumor cells.

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Diagnostic Value of Next-Generation Sequencing (NGS) and Microarray in Characterizing Tumor Origin: A Challenging and Educational Case

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