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24 April 2026 : Case report  China

Diagnostic and Treatment Strategies for Adult Non-Ossifying Fibromas: A Case Report and Literature Review

Challenging differential diagnosis, Congenital defects / diseases

Zhibin Zhao BE 1, Jiawei Li C 1, Shaoke Wu ABEFG 1*

DOI: 10.12659/AJCR.951665

Am J Case Rep 2026; 27:e951665

Figure 5 (A, B) Low-power view (H&E, ×40) of the curetted specimen confirming the lobulated architecture with fibrous septa corresponding to the septations seen on MRI. The lesion is well-circumscribed without infiltrative borders. Inset: High-power view (×200) demonstrating bland spindle cell morphology with absence of atypical mitoses and no malignant osteoid formation, definitively excluding osteosarcoma.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923