Figure 3 Outcomes measurement of RIC. (A) Out-of-bed time. (B) Trend of P0.1. (C) Trend of serum protein: albumin, prealbumin, and retinol-binding protein increased significantly after out-of-bed training. (D) Trend of inflammation markers: interleukin-6 and C-reactive protein further decreased after out-of-bed training. (E) Trend of the fraction of inspired oxygen and P/F ratio: following out-of-bed training, FiO2 progressively decreased, and P/F ratio progressively increased to a maximum of 297 mmHg. (F) Trend of motricity index: motor function continued to improve after out-of-bed training. P0.1 – oral closure pressure 0.1 seconds; P-SIMV – mechanical ventilation mode as pressure synchronized intermittent mandatory ventilation; CPAP – mechanical ventilation mode as continuous positive airway pressure; P/F ratio – arterial partial pressure of oxygen ratio fraction of inspired oxygen, as the PO2/FiO2; FiO2 – fraction of inspired oxygen; EI – endotracheal intubation; IWM – intermittent weaning from mechanical ventilation; ETT – endotracheal tube with T-tube.