29 April 2026
: Case report 
A Rare Case of Stevens-Johnson Syndrome in a Young Patient Presenting With Odynophagia Following Antibiotic Use
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease, Adverse events of drug therapy, Clinical situation which can not be reproduced for ethical reasons
John Tomasini AEF 1*, Joanna Sajdlowska
AEF 1, Gregory Crisafulli DEF 1, Hillel Ephros AE 2
DOI: 10.12659/AJCR.951823
Am J Case Rep 2026; 27:e951823
Figure 3 Severe Oral mucosal sloughing and erythemaIntraoral photograph demonstrating diffuse ulcerative and erosive lesions involving the buccal and labial mucosa. There is marked erythema, edema, and hemorrhagic crusting of the lips, with positive Nikolsky’s sign. These findings are consistent with severe mucosal involvement in SJS. Image captured under natural overhead lighting in the sagittal plane using a mobile digital camera, no staining or magnification applied.