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21 May 2026 : Case report  Mexico

A Singleton Male Infant With Aplasia Cutis Congenita Type V Associated With Single Umbilical Artery and Atrial Septal Defect: A Case Report

Challenging differential diagnosis, Unusual setting of medical care, Congenital defects / diseases, Educational Purpose (only if useful for a systematic review or synthesis)

Jesús J. Martínez-García ORCID logo AE 1,2*, Lourdes Elizabeth Zamudio-García BC 3, Melissa Martínez-Félix BC 4, Uriel A. Angulo-Zamudio DF 2, Hector Flores-Villaseñor ORCID logo DF 2, Erika Acosta-Smith ORCID logo AF 5, Adrian Canizalez-Román ORCID logo DE 2,6, Nidia León-Sicairos ORCID logo CDE 2,7

DOI: 10.12659/AJCR.951885

Am J Case Rep 2026; 27:e951885

Figure 1 Clinical presentation of Type V ACC. (A) Anterolateral view of trunk showing extensive bilateral, symmetrical skin defects on the lateral trunk and proximal lower extremities. Note the triangular morphology with apices pointing medially toward the umbilicus, consistent with vascular watershed distribution. The underlying muscle fascia is visible, covered by a thin translucent membrane. (B) Posterior view demonstrating extension of truncal lesions posteriorly along the lateral trunk. Lesions measure approximately 8×10 cm (right) and 7×9 cm (left). (C) Close-up view of right lateral trunk lesion showing well-demarcated borders with erythematous rim (2–3 mm width) and exposed underlying tissue without active bleeding. (D) Post-treatment view at day 14 showing the application of a human epidermal allograft (Epifast™) covered with a hydrocolloid dressing (DuoDERM®). Early granulation tissue formation is visible at lesion margins. ACC – aplasia cutis congenita.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923