13 July 2026
: Case report 
Coexistence of Multiple Myeloma, Mast Cell Hyperplasia, and Low-Level Myeloid Blastocytosis: A Report of a Rare Case
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Rare disease
Meng Yang BEF 1, Qian Wang D 1, Jian Zhang D 1, Hong Jiang E 1, Hongzhi Xu A 1, Kang Lu G 1, Yujie Jiang AG 1*DOI: 10.12659/AJCR.952005
Am J Case Rep 2026; 27:e952005
Figure 4 The ontogeny of hematopoietic stem cells (HSCs). All hematopoietic cells originate from HSCs. HSCs give rise to diverse blood cell types through lineage-specific differentiation. For instance, SCF supports the development of multipotent hematopoietic progenitors, whereas TPO specifically regulates megakaryocytic lineage differentiation, demonstrating the multipotency of HSCs. Moreover, cytokines act directly on HSCs to maintain the self-renewal to increase their number.