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29 April 2026 : Case report  Japan

Hemolytic Glaucoma Following Intravitreal Aflibercept Injection for Age-Related Macular Degeneration: A Case Report

Diagnostic / therapeutic accidents

Hiroki Sano ORCID logo ABDEF 1*, Ryoji Yanai ORCID logo DE 2, Yoshinori Mitamura ORCID logo DE 2

DOI: 10.12659/AJCR.952247

Am J Case Rep 2026; 27:e952247

Figure 5 Proposed mechanism of hemolytic glaucoma following intravitreal aflibercept injectionA localized vitreous-base hemorrhage at the injection site led to hemolysis and anterior migration of erythrocyte components. Obstruction of the trabecular meshwork resulted in acute intraocular pressure (IOP) elevation. Prompt surgical management, including anterior chamber irrigation and pars plana vitrectomy, successfully normalized IOP. This figure was created by the authors.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923