14 July 2026
: Case report 
Primary Small Cell Neuroendocrine Carcinoma of the Breast in a 75-Year-Old Woman With Aggressive Recurrence Despite Multimodal Therapy: A Case Report and Literature Review
Challenging differential diagnosis, Unusual setting of medical care, Rare coexistence of disease or pathology
Shefa Abdullah Alamoudi
ABCDEFG 1*, Hadeel Elwaheidi ABCDEFG 1, Hanan Albishi ABCD 2, Sarah Aldosari ABCDEFG 3, Asma M. Tulbah CD 4, Wafa Alkhayal ABCDEFG 5
DOI: 10.12659/AJCR.952443
Am J Case Rep 2026; 27:e952443
Figure 2 Contrast-enhanced bilateral digital breast tomosynthesis mammogram showing scattered fibroglandular densities with mild background parenchymal enhancement. There was a heterogeneously enhancing dense spiculated mass in the upper central mid-third of the breast with ductal extension/spicules towards the nipple (indicated by a red arrow). The mass measured 2.7×2.6×2.4 cm. There was a faint enhancing right breast retro-areolar lesion which may have been an extension from the index mass. Additionally, there was a non-enhancing circumscribed isodense nodule in the outer anterior to middle third measuring 0.6 cm.