30 May 2026
: Case report 
An Isolated Colonic Neurofibroma Without Systemic Neurofibromatosis: A Rare Case Report and Literature Review
Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Hussain Ahmed Alessa ABDEF 1*, Tahar Yacoubi DE 2, Abdulrahman Almutawa BDEF 1, Afnan Alshayeb ABDEF 3, Abdulaziz Althunayyan DE 1, Amaal Alqarfan DF 1, Saud Mohammed Alsubaie BD 1, Sarah Alomar AD 1, Fatimah Aljalal DE 1, Ayman Aledreesi BD 1, Wael Abdelgawad ABDEF 4DOI: 10.12659/AJCR.952586
Am J Case Rep 2026; 27:e952586
Figure 4 (A, B) Preoperative colonoscopy biopsies (H&E, 100× and 400×) showing a submucosal non-atypical spindle cell neurogenic lesion. (C) The lesion is positive for s100.