30 July 2026
: Case report 
Thoracic SMARCA4-Deficient Undifferentiated Tumor Presenting as a Giant Mediastinal Mass: A Case Report
Challenging differential diagnosis, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)
Nanami Ichihashi ABCDEF 1, Motona Kumagai
ABCDEF 2,3*, Miyako Shimasaki BCDEF 2, Akihiro Shioya BCDEF 3,4, Sohsuke Yamada BCDEF 3,5
DOI: 10.12659/AJCR.952937
Am J Case Rep 2026; 27:e952937
Figure 2 Histological findings on mediastinal tumor biopsy (hematoxylin and eosin staining)(A, B) Low- and intermediate-power views showing sheet-like proliferation of large undifferentiated atypical cells with focal necrosis. (C) High-power view demonstrating tumor cells with enlarged pleomorphic nuclei and rhabdoid features. No definite glandular formation or keratinization is identified.