18 July 2026
: Case report 
A 79-Year-Old Woman With Stage IIIB Lung Squamous Cell Carcinoma Presenting With Late-Onset Durvalumab‑Associated Myocarditis Requiring Differentiation From Pericardial Invasion
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Adverse events of drug therapy, Educational Purpose (only if useful for a systematic review or synthesis)
Norio Kodaka ABCDEF 1, Fumiyuki Hayashi BCE 2, Yuki Yokouchi BCE 3, Masahiro Yoshida BCE 4, Hiroto Matsuse ACDE 1*DOI: 10.12659/AJCR.953001
Am J Case Rep 2026; 27:e953001
Figure 1 (A) Chest CT at diagnosis (April/202X): A large tumor is observed in contact with the pericardium, although CT alone cannot determine whether myocardial invasion is present. (B) Chest CT after concurrent chemoradiotherapy (CCRT) (September/202X): The tumor has shrunk, and only a small shadow remains after CCRT was performed; this indicates a therapeutic effect of CCRT. (C) Chest CT at the onset of myocarditis as an irAE (May/202X+1): circumferential pericardial effusion and predominantly right-sided pleural effusion are observed.