06 July 2026
: Case report 
Diagnostic Challenge of Sequential Appendicitis in a Patient With Appendiceal Duplication: A Case Report
Congenital defects / diseases
Adonys Hidalgo López
ABCDEFG 1, Héctor Rafael Ochomogo García ABCDEFG 2, Juan Sebastian Asteguieta Castillo ABCDEFG 1*, Carlos Diaz Q ABCDEFG 1
DOI: 10.12659/AJCR.953106
Am J Case Rep 2026; 27:e953106
Figure 2 Histopathological confirmation of sequential acute appendicitis(A) Hematoxylin and eosin-stained section of the appendix obtained during the first intervention, demonstrating extensive mucosal necrosis with loss of surface epithelium and diffuse acute inflammatory infiltrate predominantly composed of neutrophils. The inflammatory process involves the mucosa, submucosa, muscularis propria, and serosa, consistent with transmural acute appendicitis. (B) Histological section of the second appendix resected during the subsequent intervention, revealing similar transmural acute inflammatory changes with marked serosal congestion, fibrinopurulent exudate, and focal disruption of the appendiceal wall consistent with perforated acute appendicitis.