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01 August 2026 : Case report  China

Continuous Epidural Infusion of Hydroxyethyl Starch for Spontaneous Intracranial Hypotension: A Retrospective Case Series

Challenging differential diagnosis, Rare disease

Xiao-Yan Zhang ORCID logo ABEF 1,2,3, Qiu-Li Zhang CEF 1,2,3, Ying Liu B 1,2,3, Li-Jie Zhu B 1,2,3, Ying-Zhi Li B 1,2,3, Xi-Ying Ye F 4, Zhong-Jun Zhang ACD 4*, Yao-Xian Zhang ACD 1,2,3

DOI: 10.12659/AJCR.953129

Am J Case Rep 2026; 27:e953129

Figure 1 (A) Brain T1 gadolinium-enhanced MRI demonstrating diffuse, continuous, linear enhancement of pachymeninges (blue arrow). (B) Brain T2-weighted MRI revealing bilateral subdural effusions (blue arrow). (C) Preoperative brain CT illustrating bilateral frontoparietal and temporal chronic SDHs, predominantly on the right side (blue arrow, maximum thickness of SDH: 11 mm). (D) Brain CT on postoperative day 2 following burr-hole drainage of bilateral frontoparietal and temporal SDHs, indicating an improvement of bilateral frontoparietal and temporal subdural effusions and hemorrhage compared with those in the anterior regions (blue arrow). (E) Brain CT at discharge showing no evidence of hematoma recurrence (blue arrow). (F) Brain CT conducted 1 month after discharge displaying no hematoma recurrence (blue arrow).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923